
KPV
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Key Health Benefits:
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Supports a healthy inflammatory response
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Improves gut lining integrity and intestinal barrier function
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Helps modulate immune signaling in gut and skin tissues
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Supports skin comfort and tissue repair in inflammatory-stress models
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Commonly used for gut inflammation, skin irritation, and gut barrier-defense research
Need supplies?
Get all the reconstitution & injection supplies.
Bacteriostatic Water$12.50
Injection Syringes$16.50
Alcohol Pads$8.90
About KPV
KPV (Lys-Pro-Val) is the C-terminal tripeptide sequence of alpha-melanocyte-stimulating hormone (alpha-MSH), a naturally occurring immunomodulatory peptide. KPV is studied for inflammatory signaling, intestinal barrier integrity, antimicrobial activity, and barrier-tissue support in gut and skin research models. In published models, KPV is transported into epithelial and immune cells through PepT1 and has been associated with lower NF-kB/MAPK inflammatory signaling and downstream cytokine activity.
This product is intended solely for research purposes and all product information provided on this website is intended for educational purposes only.
Peer-reviewed studies on KPV
- Dalmasso G, Charrier-Hisamuddin L, Nguyen HTT, et al. (2008). PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation. Gastroenterology.Read source ↗
- Xiao B, Laroui H, Ayyadurai S, et al. (2017). Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis. Molecular Therapy.PMID 28143741Read source ↗
- Cutuli M, Cristiani S, Lipton JM, Catania A (2000). Antimicrobial effects of alpha-MSH peptides. Journal of Leukocyte Biology.PMID 10670585Read source ↗
- Brzoska T, Luger TA, Maaser C, Abels C, Bohm M (2008). alpha-MSH related peptides: a new class of anti-inflammatory and immunomodulating drugs. Annals of the Rheumatic Diseases.Read source ↗
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Peptides are research compounds and are not approved for human use unless prescribed by a licensed medical practitioner.
