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Pantheon Peptides
Peptide Stacks & Cycles

Sermorelin GHRP-2 5mg 5mg

Updated April 28, 2026


Primary Benefits

  • Increases natural, pulsatile growth hormone (GH) release
  • Promotes lean muscle growth and body fat reduction
  • Accelerates recovery from physical exertion or injury
  • Enhances sleep quality and circadian rhythm regulation
  • Supports mood, energy, and regenerative pathways associated with IGF-1

Mechanism of Action

This classic GH combo blends Sermorelin and GHRP-2 to engage both major growth hormone pathways:

  • Sermorelin is a GHRH analog that stimulates the pituitary to secrete growth hormone. It restores natural GH rhythms and promotes downstream IGF-1 production for anabolic and metabolic effects.
  • GHRP-2 is a potent GHRP (Growth Hormone Releasing Peptide) that binds to ghrelin receptors, triggering additional GH release. It synergizes with GHRH analogs like Sermorelin to amplify GH pulses and metabolic signaling.

Together, they deliver a multi-phase GH release — one that mimics youthful secretion patterns for superior fat-burning, sleep, and recovery support.

Dosing & Protocol

Subcutaneous (SQ) Injection:
Can be combined in one syringe. Administer into the lower abdomen on an empty stomach.

Sermorelin – 5mg Vial

  • Reconstitution: 2.5 ml bacteriostatic water
     (= 200–400 mcg per 10–20 units)
  • Daily Dose: 200–400 mcg (10–20 units)
  • Cycle:
     5 days on / 2 days off
     4 to 5 weeks
  • Timing: First thing in the morning, 2 hours after eating, or before bedtime on an empty stomach

GHRP-2 – 5mg Vial

  • Reconstitution: 3.0 ml bacteriostatic water
     (= 166 mcg per 10 units)
  • Daily Dose: 166 mcg (10 units)
  • Cycle:
     5 days on / 2 days off
     6–12 weeks on, 2–4 weeks off
  • Timing: Ideally taken with Sermorelin at bedtime or morning dosing window

Potential Side Effects

Sermorelin:

  • Temporary injection site irritation
  • Headache or fatigue (rare)
  • Mild water retention or joint stiffness

GHRP-2:

  • Slight water retention or flushing
  • Temporary hunger increase (less than GHRP-6)
  • Rare elevation in cortisol or prolactin in sensitive users

Who Is This Stack For?

  • Adults over 30 with declining GH levels seeking natural hormone support
  • Fitness enthusiasts aiming to enhance body composition and recovery
  • Individuals with poor sleep, low energy, or slowed physical recovery
  • Biohackers and wellness seekers interested in safe GH optimization
  • Those looking for a cost-effective and proven GH-stimulating protocol

Notes

  • Avoid food intake 90–120 minutes before and after injection
  • Store reconstituted peptides in the refrigerator; use within 45 days unless the product label or protocol says otherwise
  • Can be taken once daily at night or split between morning and night for customized timing
  • Rotate injection sites to avoid irritation
  • Monitor IGF-1 or blood glucose markers if using long-term

Disclaimer:
The information provided in this article is for educational and informational purposes only and is not intended as medical advice. These statements have not been evaluated by the FDA or Health Canada. Peptides and other compounds discussed are intended for research purposes only and are not approved for human consumption unless prescribed by a licensed medical professional. Always consult your healthcare provider before starting any new protocol, supplement, or treatment.